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←West - 121 Esplanade-River Towards Union Station
Jack Layton Way at St Matthews Rd
St Matthews Rd at Gerrard St East
Gerrard St East at River St
River St
Dundas St East South Side
King St East
Bayview Ave at Front St East
Mill St
Cherry St West Side
Trinity St
Parliament St
Berkeley St at Front St East South Side
The Esplanade    . . .    The Esplanade
Princess St
Lower Sherbourne St
Lower Jarvis St
Church St West Side
Yonge St
Yonge St at Front St East
1 Front St West - Union Station
→East - 121 Esplanade-River Towards Hennick Bridgepoint Hospital
1 Front St West - Union Station
Church St at The Esplanade
The Esplanade at Lower Jarvis St East Side
The Esplanade at Lower Sherbourne St
Princess St at The Esplanade North Side
Front St East
Berkeley St
Parliament St
Cherry St
Bayview Ave
River St
Queen St East
Dundas St East
Gerrard St East
Gerrard St East at Blackburn St
Jack Layton Way at Blue Rodeo Dr
Jack Layton Way at St Matthews Rd

Additional Stops:

121 Temporary route change due to New Years Eve 2025 events
121esplanade-river–Temporary route change due to New Year's Eve 2025 events
December 31, 2025 - 11:30 PM to January 1, 2026 - 02:00 AM
121 Temporary route change due to sewer upgrades
121esplanade-river–121 Temporary route change due to sewer upgrades
November 24, 2025 - 07:00 AM to February 7, 2026